← All articles

Historical sample · This article is not presented as new evidence this week.

Randomized trialNew England Journal of Medicine

Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults

First online Jun 16, 2023On EM Weekly Oct 26, 2026Discovered Oct 26, 2026AI-generated Not yet human-reviewed

Summary

In 1,417 critically ill adults, video laryngoscopy achieved first-pass success in 85.1% versus 70.8% with direct laryngoscopy (difference 14.3 percentage points; 95% CI 9.9 to 18.7). Severe complications occurred in 21.4% versus 20.9% (difference 0.5 points; 95% CI -3.9 to 4.9).

Why it matters

Video laryngoscopy improved first-pass success in ED and ICU intubations, largely performed by trainees; complication benefit was not demonstrated.

Study at a glance

Design
Randomized trial
Population
Critically ill adults in 17 US EDs and ICUs.
Sample size
1417
Intervention
Video laryngoscopy
Comparator
Direct laryngoscopy
Primary endpoint
Successful intubation on the first attempt

Main findings

  • First-pass success: 600/705 vs 504/712.
  • Severe complications: 151/705 vs 149/712.

Limitations

Stopped early for efficacy. Most operators were residents or fellows, limiting generalization to experienced operators.

Read the primary source

Full text: Open-access full text available.

Original source

DOI: 10.1056/NEJMoa2301601

PMID: 37326325

Source retrieved Oct 26, 2026. Abstract reviewed; full-text access was not used.

Corrections & review history

No corrections recorded. Human review: not yet human-reviewed.